‘Malaria drug is biggest hope against coronavirus’

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Reuters
Published : 15:11, Mar 29, 2020 | Updated : 15:11, Mar 29, 2020

FILE PHOTO: Novartis CEO Vas Narasimhan addresses the Swiss drugmaker`s annual news conference in Basel, Switzerland, Jan 30, 2019. REUTERSNovartis Chief Executive Vas Narasimhan said his Sandoz generics unit's malaria, lupus and arthritis drug hydroxychloroquine is the company's biggest hope against the coronavirus, Swiss newspaper SonntagsZeitung reported on Sunday.

Novartis has pledged to donate 130 million doses and is supporting clinical trials needed before the medicine, which U.S. President Donald Trump also has been promoting, can be approved for use against the coronavirus.

File photo: Researchers at the University of Minnesota Genomics Center set up an automated liquid handler as researchers begin a trial to see whether malaria treatment hydroxychloroquine can prevent or reduce the severity of the coronavirus disease (COVID-19), at the University of Minnesota in Minneapolis, Minnesota, US Mar 19, 2020. ReutersOther companies including Bayer and Teva have also agreed to donate hydroxychloroquine or similar drugs, while Gilead Sciences is testing its experimental drug remdesivir against coronavirus.

"Pre-clinical studies in animals as well as the first data from clinical studies show that hydroxychloroquine kills the coronavirus," Narasimhan told the newspaper. "We're working with Swiss hospitals on possible treatment protocols for the clinical use of the drug, but it's too early to say anything definitively."

He said the company is currently looking for additional active drug ingredients to make more hydroxychloroquine, should clinical trials be successful.

Narasimhan said three other Novartis drugs - Jakavi for cancer, multiple sclerosis drug Gilenya and fever drug Ilaris - are being studied for their effect on complications related to COVID-19, the newspaper reported. This follows separate efforts to re-purpose drugs made by companies including Roche and Sanofi to treat complications related to the disease.

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